Forensic Science International Supplement Series
Volume 1, Issue 1 , Pages 11-14 , December 2009

The modern trends in alcohol, drugs and driving research

  • Elke Raes

      Affiliations

    • Department of Clinical Chemistry, Microbiology and Immunology, Ghent University, Belgium
    • Corresponding Author InformationCorresponding author. Tel.: +32 9 332 34 07; fax: +32 9 332 49 85.
    • ,
  • Kristof Pil

      Affiliations

    • Department of Clinical Chemistry, Microbiology and Immunology, Ghent University, Belgium
    • ,
  • Alain G. Verstraete

      Affiliations

    • Department of Clinical Chemistry, Microbiology and Immunology, Ghent University, Belgium
    • Laboratory of Clinical Biology - Toxicology, Ghent University Hospital, Ghent, Belgium

Received 21 July 2009 ,Accepted 24 July 2009.

References 

  1. E. Raes, T. Van den Neste, A.G. Verstraete, EMCDDA insights: drugs and driving: latest developments and findings from research since 1999, Lisbon, 2009.
  2. Ramaekers JG, Kauert G, van Ruitenbeek P, Theunissen EL, Schneider E, Moeller MR. High-potency marijuana impairs executive function and inhibitory motor control. Neuropsychopharmacology. 2006;31:2296–2303
  3. King LA. EMCDDA Insights: An Overview of Cannabis Potency in Europe. Lisbon: EMCDDA; 2004;
  4. Rush CR, Baker RW, Wright K. Acute physiological and behavioral effects of oral cocaine in humans: a dose–response analysis. Drug Alcohol Depend. 1999;55:1–12
  5. Higgins ST, Bickel WK, Hughes JR, Lynn M, Capeless MA, Fenwick JW. Effects of intranasal cocaine on human learning, performance and physiology. Psychopharmacology. 1990;102:451–458
  6. Stillman R, Jones RT, Moore D, Walker J, Welm S. Improved performance 4 hours after cocaine. Psychopharmacology. 1993;110:415–420
  7. Mattay VS, Callicott JH, Bertolino A, Heaton I, Frank JA, Coppola R. Effects of dextroamphetamine on cognitive performance and cortical activation. Neuroimage. 2000;12:268–275
  8. Swerdlow NR, Stephany N, Wasserman LC, Talledo J, Shoemaker J, Auerbach PP. Amphetamine effects on prepulse inhibition across-species: replication and parametric extension. Neuropsychopharmacology. 2003;28:640–650
  9. Berghaus G, Ramaekers JG, Drummer OH. Demands on scientific studies in different fields of forensic medicine and forensic sciences – Traffic medicine – Impaired driver: alcohol, drugs, diseases. Forensic Sci. Int. 2007;165:233–237
  10. Sexton BF, Tunbridge RJ, Board A, Jackson PG, Wright K, Stark MM. TRL: 543. The Influence of Cannabis and Alcohol on Driving. TRL 543. Road Safety Division, Department of the Environment, Transport and the Regions; 2002;
  11. J.G. Ramaekers, K.P.C. Kuypers, C.M. Wood, G.R.J. Hockey, S. Jamson, H. Jamson. IMMORTAl Deliverable D-R4.4: experimental studies on the effects of licit and illicit drugs on driving performance, psychomotor skills and cognitive function, 2004.
  12. Hoffman WF, Moore M, Templin R, McFarland B, Hitzemann RJ, Mitchell SH. Neuropsychological function and delay discounting in methamphetamine-dependent individuals. Psychopharmacology. 2006;188:162–170
  13. Johanson CE, Frey KA, Lundahl LH, Keenan P, Lockhart N, Roll J. Cognitive function and nigrostriatal markers in abstinent methamphetamine abusers. Psychopharmacology. 2006;185:327–338
  14. Monterosso JR, Aron AR, Cordova X, Xu JS, London ED. Deficits in response inhibition associated with chronic methamphetamine abuse. Drug Alcohol Depend. 2005;79:273–277
  15. Salo R, Nordahl TE, Moore C, Waters C, Natsuaki Y, Galloway GP. A dissociation in attentional control: evidence from methamphetamine dependence. Biol. Psychiatry. 2005;57:310–313
  16. Chou YH, Huang WS, Wan FJ, Lu RB, Cheng CY, Wey SP. Dopamine transporters and cognitive function in methamphetamine abuser after a short abstinence: a SPECT study. Neuroimage. 2004;22:T143
  17. Newton TF, Kalechstein AD, Hardy DJ, Cook IA, Nestor L, Ling W. Association between quantitative EEG and neurocognition in methamphetamine-dependent volunteers. Clin. Neurophysiol. 2004;115:194–198
  18. Salo R, Nordahl TE, Possin K, Leamon M, Gibson DR, Galloway GP. Preliminary evidence of reduced cognitive inhibition in methamphetamine-dependent individuals. Psychiatry Res. 2002;111:65–74
  19. Chang L, Ernst T, Speck O, Patel H, DeSilva M, Leonido-Yee M. Perfusion MRI and computerized cognitive test abnormalities in abstinent methamphetamine users. Psychiatry Res. Neuroim. 2002;114:65–79
  20. Volkow ND, Chang L, Wang GJ, Fowler JS, Leonido-Yee M, Franceschi D. Association of dopamine transporter reduction with psychomotor impairment in methamphetamine abusers. Am. J. Psychiatry. 2001;158:377–382
  21. Simon SL, Domier C, Carnell J, Brethen P, Rawson R, Ling W. Cognitive impairment in individuals currently using methamphetamine. Am. J. Addict. 2000;9:222–231
  22. Mura P, Chatelain C, Dumestre V, Gaulier JM, Ghysel MH, Lacroix C. Use of drugs of abuse in less than 30-year-old drivers killed in a road crash in France: a spectacular increase for cannabis, cocaine and amphetamines. Forensic Sci. Int. 2006;160:168–172
  23. Mathijssen MPM. Drug-, medicijn- en alcoholgebruik van automobilisten in Nederland 1997/1998. R-99-5. Leidschendam, Stichting Wetenschappelijk Onderzoek Verkeersveiligheid SWOV; 1999;
  24. Christophersen AS. The occurrence of drugged driving in Norway—existing problems and solutions. Blutalkohol. 2000;37:20–27
  25. Augsburger M, Donze N, Menetrey A, Brossard C, Sporkert F, Giroud C. Concentration of drugs in blood of suspected impaired drivers. Forensic Sci. Int. 2005;153:11–15
  26. Ramaekers JG, Berghaus G, van Laar MW, Drummer OH. Dose related risk of motor vehicle crashes after cannabis use. Drug Alcohol Depend. 2004;73:109–119
  27. Plaut O, Staub C. Driving under the influence of drugs in the canton of Geneva, Switzerland. Results and roadside survey project. In:  Laurel H,  Schlyter H editor. Proceedings of the 15th International Conference on Alcohol, Drugs and Traffic Safety. Stockholm, Sweden. 2000;
  28. Logan BK, Schwilke EW. Changing patterns of alcohol and drug use in fatally injured drivers in Washington State 1992–2002. In:  Oliver J,  Williams P,  Clayton A editor. The 17th International Conference on Alcohol, Drugs and Traffic Safety. Glasgow, Scotland, UK. 2004;
  29. Logan BK. Adverse effects of stimulants and cannabis on driving. In: 17th Meeting of the International Association of Forensic Sciences. Hong Kong, China. 2005;
  30. Longo MC, Hunter CE, Lokan RJ, White JM, White MA. The prevalence of alcohol, cannabinoids, benzodiazepines and stimulants amongst injured drivers and their role in driver culpability. Part I. The prevalence of drug use in drive the drug-positive group. Accid. Anal. Prev. 2000;32:613–622
  31. del Rio MC, Gomez J, Sancho M, Alvarez FJ. Alcohol, illicit drugs and medicinal drugs in fatally injured drivers in Spain between 1991 and 2000. Forensic Sci. Int. 2002;127:63–70
  32. Assum T, Mathijssen MPM, Houwing S, Buttress SC, Sexton B, Tunbridge RJ. IMMORTAL Deliverable D-R4.2: The Prevalence of Drug Driving and Relative Risk Estimations. A Study Conducted in the Netherlands, Norway and United Kingdom. 2005;
  33. Brault M, Dussault C, Bouchard J, Lemire AM. The contribution of alcohol and other drugs among fatally injured drivers in Québec: final results. In:  Oliver J,  Williams P,  Clayton A editor. The 17th International Conference on Alcohol, Drugs and Traffic Safety. Glasgow, United Kingdom. 2004;
  34. Morland J. The Norwegian roadside study on alcohol and drugs. Borkenstein Course: The Effects of Drugs on Human Performance and Behavior, April 13th–18th. Indiana University, Robert F. Borkenstein Center for Studies of Law in Action; 2008;
  35. E. Raes, A. Verstraete, P. Lillsunde, T. Gunnar, M. Laloup, A.S. Christophersen, M. Moeller, K. Hammer, Relationship between oral fluid and blood concentrations of drugs of abuse in drivers suspected of DUID, Proceedings of the Société Française de Toxicologie Analytique (SFTA) 16th annual meeting, The International Association of Forensic Toxicologists (TIAFT) 46th international meeting & Society of Hair Testing (SoHT) Annual Meeting Martinique, June 2–8, 2008. Ann. Toxicol. Anal. 20 (2008) 33–34.
  36. Engblom C, Gunnar T, Rantanen A, Lillsunde P. Driving under the influence of drugs–amphetamine concentrations in oral fluid and whole blood samples. J. Anal. Toxicol. 2007;31:276–280
  37. Krüger HP, Schultz E, Magerl H. The German roadside survey 1992–1994. Saliva analyses from an unselected driver population: licit and illicit drugs. In:  Kloeden C,  McLean AJ editor. The 13th International Conference on Alcohol, Drugs and Traffic Safety. Adelaide, Australia: NHMRC Road Accident Research Unit, University of Adelaide. 1995;
  38. K. Pil, E. Raes, A. Verstraete. Preliminary method for simultaneous quantification of psychoactive substances in oral fluid using UPLC–MS/MS. Proceedings of the Société Française de Toxicologie Analytique (SFTA) 16th Annual Meeting, The International Association of Forensic Toxicologists (TIAFT) 46th International Meeting & Society of Hair Testing (SoHT) Annual Meeting. Martinique June 2–8, 2008. Ann. Toxicol. Anal. 20 (2008) 22.
  39. W. Lechowicz, M. Kala, J. Walker, Screening and quantification of the twenty-four drugs in oral fluid relevant for road traffic safety by means of liquid chromatography tandem mass spectrometry with electrospray ionisation, Proceedings of the Joint meeting of the International Association of Forensic Toxicologists (TIAFT) and International Council on Alcohol, Drugs and Traffic Safety (ICADTS) and featuring the 8th Ignition Interlock Symposium (IIS). Seattle August 26–30, 2007. Ann. Toxicol. Anal. 14 (2007) 324.
  40. Concheiro M, de Castro A, Quintela O, Cruz A, Lopez-Rivadulla M. Determination of illicit and medicinal drugs and their metabolites in oral fluid and preserved oral fluid by liquid chromatography–tandem mass spectrometry. Anal. Bioanal. Chem. 2008;391:2329–2338
  41. Oiestad EL, Johansen U, Christophersen AS. Drug screening of preserved oral fluid by liquid chromatography–tandem mass spectrometry. Clin. Chem. 2007;53:300–309
  42. Walsh JM, Verstraete A, Huestis MA, Morland J. Guidelines for research on drugged driving. Addiction. 2008;103:1258–1268
  43. www.druid-project.eu2008;
  44. J.H. Lacey, T. Kelley-Baker, D. Furr-Holden, K. Brainard, C. Moore, Pilot test of new roadside survey methodology for impaired driving, DOT HS 810 704, NHTSA, 2007.

PII: S1875-1741(09)00005-6

doi: 10.1016/j.fsisup.2009.07.004

Forensic Science International Supplement Series
Volume 1, Issue 1 , Pages 11-14 , December 2009

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